ACOG - Noninvasive Prenatal Testing for Fetal Aneuploidy

Noninvasive prenatal testing that uses cell free fetal DNA from the plasma of pregnant women offers tremendous potential as a screening tool for fetal aneuploidy. Circulating cell free fetal DNA, which comprises approximately 3–13% of the total cell free maternal DNA, is thought to be derived primarily from the placenta, and is cleared from the maternal blood within hours after childbirth (1). Recently, cell free fetal DNA analysis has become clinically available for women at increased risk of fetal aneuploidy...


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